In this chapter, Nephi is prophesying about the events surrounding the coming forth of the Book of Mormon. He describes the time that they took copies of some of the characters and their translation to professor Charles Anthon, who certified that the translation was correct, but upon finding that the book was claimed to be of divine origin, rescinded his certification and also claimed that if the book was sealed, he couldn't read it.
The verse I've quoted above describes, in contrast, the Lord delivering the book to Joseph Smith, an uneducated young man. I'm sure his reaction, when told he would need to translate the golden plates, was something like "I am not learned. How can I do this thing?"
This is the Lord's response. Pay attention because it is more than just good advice to Joseph Smith.
"Then shall the Lord God say unto him: The learned shall not read them, for they have rejected them, and I am able to do mine own work; wherefore thou shalt read the words which I shall give unto thee. (2 Nephi 27:20)
I love the phrase here: "I am able to do mine own work". The truth is, God is all-knowing and all-powerful. He could have just delivered the book pre-translated to Joseph. But it was through the translation process that Joseph learned so much.
This should come as a great comfort to those who feel inadequate to do what they are asked to do. So often, the first feeling that comes over someone upon receiving a new calling, is a sense of inability to do what is required. This passage should be a comfort in a couple of ways. First, the Lord could have done this work himself, yet he called you. You must have something to offer. Second, if the Lord can do it himself, he certainly can help you. Trust Him. Lean on Him. He will be there.